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Identification and validation of novel pharmaceutical drug targets for cardiovascular disease (since 2013)

Cardiovascular disease (CVD), including high blood pressure, coronary artery disease, heart disease and stroke, is the leading cause of death in the world. To improve the life-expectancy of CVD patients, the multi-partner, FP7-funded consortium CarTarDis (Cardiovascular Target Discovery) set out to advance the development of CVD medicines by discovery and validation of novel therapeutics targets to CVD.

PolyGene plays an important role by supplying partners with target validation models of both, already defined novel target genes, and additional targets emerging in the ongoing consortiums’ screenings; on the other hand, PolyGene is able to improve its competitive position by establishing heart-specific gene regulation systems based on our exclusive tools of hormone and antibiotic regulation.

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