A point mutation in a heart-relevant gene seems to be linked to arrhythmia – can we confirm this in a mouse model? Within a patient study, an overexpressed gene is found to be linked to cancer – does suppressing it prevent a mouse from getting cancer?

Well-designed mouse models give clear-cut explanations, validate targets in the pharma discovery process, or hypotheses in academic research, and deliver surprising and novel insights that would not be possible otherwise.

Generating them: this is profoundly ethical, deeply complex and interesting, greatly captivating, and fundamentally relevant.

We share your fervor and engagement and are proud to partake in your research!

The Swiss way! You expect quality, and you are entitled to it. We will have sleepless nights if anything doesn’t run smoothly, and we can’t be satisfied if you as a customer are not perfectly happy. Our business is tricky – we know that acting wisely, quickly, and decidedly is what we are called upon constantly, any day: with highest quality infrastructure and best-educated staff. And since we’re efficient, we can also beat low prices.

And of course, we know that just as much as good science, our business is also excellent communication and good relationships to scientists and colleagues.

• Great news for PolyGene and collaborators under the same purpose October 2, 2017 polygene

  PolyGene AG, together with TargetEx Kft. (Hungary), Intelligent Pharma (Spain) and University of Zürich (Switzerland), received European funding to continue PolyGene’s ambitious research program on gene regulation tools, and to successfully bring these expression systems to the market.

  SwitchItOn will generate a toolbox of novel genomic switches, opening new avenues of ...

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• One step closer to understanding T-cell leukemia August 9, 2017 polygene

  T-cell leukemia is rare blood cancer in the own immune system. T-cell acute lymphoblastic leukemia, a special form of T-cell leukemia, was investigated by Belgian researchers with striking findings.

  In a recently conducted patient study, a R98S mutation in ribosomal protein L10 recurred in 8% of children with T-cell acute lymphoblastic leukemia.

  This protein plays ...

  » read more

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