PolyGene offers a microsatellite-based genotyping and backcrossing service for users of genetically modified mice, and mouse breeders.
GenoMouse Speed Congenics is a carefully established and flexible tool for optimising the backcrossing process in congenic mouse breedings, reducing valuable time as compared with conventional backcrossing.
GenoMouse is also a valuable tool for genetic background testing in strain quality control. PolyGene‘s GenoMouse service is readily available for five commonly used mice combinations (B6/DBA2, B6/129, B6/BalbC, B6/NOD, and B6/FVB) and can be customized for additional mouse strain pairs in 3-5 weeks.
PolyGene offers these services for customer-delivered genomic samples, as well as within a breeding program at the PolyGene laboratories. For the latter, PolyGene can accomodate the embryo transfer into its own unit, and subsequent breeding, genotyping and health control according to FELASA protocols.
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